Naturally-occurring isoflavone phytonutrients with Vitamin D3 and citrate-malate source calcium and magnesium

• Extensive basic and clinical data on the isoflavone derivative ipriflavone suggests that it is a safe and efficacious alternative to estrogen therapy for increasing bone mass in postmenopausal women. (Menopause 1999 6(3):233-41)
• Calcium, as the citrate/malate salt, has been shown to be a preferred form of calcium supplement and to reduce bone loss in postmenopausal women. (N Engl J Med 1990 Sept; 323(13):878-83)
• Vitamin D is the precursor of 1, 25 dihydroxycholecalciferol, an extremely potent hormone that promotes the intestinal absorption of calcium. Vitamin D supplementation can augment the favorable effect of calcium supplementation on bone health in postmenopausal women. (Amer J Clin Nut 1995 May;61(5):1140-45)
• Vitamin K, interacting with calcium and possibly vitamin D, has an important role in the maintenance of bone formation and bone density. (Osteoporos Int. 1999;9 Suppl 2:S48-52)
• Normal boron nutritional status is beneficial for optimal calcium and bone metabolism. (Am J Clin Nutr 1995 Feb;61(2):341-5)