Cryptolepis sanguinolenta is a plant found traditionally in Ghana and other regions of Africa. It helps maintain normal inflammatory balance and microbial balance and provides antioxidant support for those with high spirochete load.

Spirochetes are bacteria that are usually spread by tick bites, and they are often accompanied by other associated microbes that can make recovery especially challenging. Cryptolepis and its main alkaloid, cryptolepine, have shown microbial balancing activity for inhibiting unwanted bacterial organisms. Furthermore, cryptolepine has demonstrated potent activity against spirochetes. In another study, Cryptolepis showed strong activity against both growing and non-growing stationary phase spirochetes.