Pure EncapsulationsNrf2 Detox60Veggie Caps
Item #:
32814
UPC:
766298017624
Pure EncapsulationsNrf2 Detox60Veggie Caps
Item #:
32814
UPC:
766298017624
Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org*
- Supports detoxification and antioxidant defenses on a cellular level*
- Helps maintain healthy cells and tissues*
- Made with vegan ingredients
Nrf2 Detox is a three-ingredient detox formula designed to help stimulate detoxification and support antioxidant defenses. Nrf2 Detox specifically supports detoxification processes in the liver and promotes proper enzyme function, transport, and cell maturation.*
Nrf2 and detoxification support*
Cruciferous vegetables of the brassica family have long been recognized for their ability to support detoxification thereby maintaining healthy cells and tissues. Cruciferous vegetables, like broccoli, cauliflower, Brussels sprouts and kale, are the richest sources of glucosinolates, which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed. The isothiocyanate sulforaphane is one of the most powerful activators of phase II enzyme function in the liver, supporting toxin elimination. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports robust, long-lasting expression of numerous genes responsible for detoxification and protection against oxidative stress. Among these genes are glutathione peroxidase, superoxide dismutase and various phase II enzymes, such as glutathione sulfotransferases. Nrf2 also supports expression of glutathione glutamylcysteinyl ligase, which is responsible for a critical step in the biosynthesis of glutathione, a vital component of cellular antioxidant and detoxification systems. Found in virtually every cell of the body, glutathione plays essential roles in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation. Optimal levels of glutathione have been associated with physical and mental health. The highest concentration of glutathione is found in the liver, where it offers antioxidant support, protects tissue and maintains detoxification. In a randomized clinical trial, supplementation with 250 and 1,000 mg of Setria® glutathione per day increased glutathione levels in the blood after one, three and six months. At six months, mean glutathione levels in the high-dose group increased 30-35% in erythrocytes, plasma and lymphocytes, and 260% in buccal cells (P<0.05). In the low-dose group, mean glutathione levels increased 17% and 29% in blood and erythrocytes, respectively (P<0.05). Both glutathione dose groups showed support for antioxidant defenses, indicated by decreases in the oxidized-to-reduced-glutathione ratio in whole blood after six months.*
Three-ingredient combination designed to support detoxification and antioxidant defenses.*
Setria® is a registered trademark of KYOWA HAKKO BIO Co., Ltd.
resVida® This product contains resVida®. resVida® is a registered trademark of DSM Nutritional Products, Inc.
Uses For Nrf2 Detox Detoxification: Cruciferous vegetables of the brassica family have long been recognized for their ability to support detoxification thereby maintaining healthy cells and tissues. Cruciferous vegetables, like broccoli, cauliflower, Brussels sprouts and kale, are the richest sources of glucosinolates, which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed. The isothiocyanate sulforaphane is one of the most powerful activators of phase II enzyme function in the liver, supporting toxin elimination. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports robust, long-lasting expression of numerous genes responsible for detoxification and protection against oxidative stress. Among these genes are glutathione peroxidase, superoxide dismutase and various phase II enzymes, such as glutathione sulfotransferases. Nrf2 also supports expression of glutathione glutamylcysteinyl ligase, which is responsible for a critical step in the biosynthesis of glutathione, a vital component of phase II detoxification. The highest concentration of glutathione is found in the liver, where it offers antioxidant support, protects tissue and maintains detoxification.* Cellular Health: Glutathione is also a vital component of cellular antioxidant systems. Found in virtually every cell of the body, glutathione plays essential roles in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation. Optimal levels of glutathione have been associated with physical and mental health. In a randomized clinical trial, supplementation with 250 and 1,000 mg of Setria® glutathione per day increased glutathione levels in the blood after one, three and six months. At six months, mean glutathione levels in the high-dose group increased 30–35% in erythrocytes, plasma and lymphocytes, and 260% in buccal cells (P<0.05). In the low-dose group, mean glutathione levels increased 17% and 29% in blood and erythrocytes, respectively (P<0.05). Both glutathione dose groups showed support for antioxidant defenses, indicated by decreases in the oxidized-toreduced-glutathione ratio in whole blood after six months.* What Is The Source? Broccoli sprout concentrate is a 20:1 extract derived from Brassica oleracea italica and standardized to contain a minimum of 1,000 mcg sulforaphane. Glutathione is sourced from corn glucose fermentation. Resveratrol is synthetic.
Supplemental Facts
- Amount Per Serving
- each vegetarian capsule contains:
- Broccoli (Brassica oleracea italica) sprout concentrate (whole plant)250 mg
-
- (standardized to contain 1,000 mcg sulforaphane)
- Setria® glutathione (reduced form)250 mg
- resVida® resveratrol (as trans-resveratrol)15 mg
- other ingredients: vegetarian capsule (cellulose, water)
- 1 capsule, 1-3 times daily, with meals.
- 1 capsule, 1-3 times daily, with meals.
Are There Any Potential Side Effects Or Precautions?
If pregnant or lactating, consult your physician before taking this product. It is recommended to use resveratrol cautiously in patients with hormonal disorders and those using estrogen therapy, as resveratrol may act as either an estrogen agonist or estrogen antagonist. Consult your physician for more information.
Are There Any Potential Drug Interactions?
Some studies have reported that broccoli sprout extract can affect the way that the liver breaks down medications metabolized by the cytochrome P450 system, altering the effects of these medications and possibly the dose needed for treatment. Resveratrol and broccoli sprout extract may react with blood thinning medications. Consult your physician for more information.
Write Your Own Review